Three-month mortality rate and clinical predictors in patients with venous thromboembolism and cancer. Findings from the RIETE registry
Three-month mortality rate and clinical predictors in patients with venous thromboembolism and cancer. Findings from the RIETE registry
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DOI：
10.1016/j.thromres.2012.10.007
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发表时间：
2013-01-01
影响因子：
7.5
通讯作者：
Monreal, Manuel
中科院分区：
文献类型：
--
作者：
Gussoni, Gualberto;Frasson, Stefania;Monreal, Manuel
静脉血栓栓塞症(VTE)的患者，特别是癌症患者，复发、大出血和短期/中期死亡率的风险增加。来自35,539名患者(其中6,075名癌症患者)的数据在过去三个月出现症状VTE并登记在全球RIETE登记中，评估总体和肺血栓(PE)相关死亡率及其潜在预测因素，特别是癌症患者。在RIETE总人口中，总的3个月死亡率为7.9%，死亡被认为与PE相关的为1.4%。癌症患者的死亡率(26.4%)显著高于非癌症患者(4.1%，P
Patients with venous thromboembolism (VTE), and particularly those with cancer, are at increased risk of recurrences, major bleeding, and short- / medium-term mortality.Data from 35,539 patients (6,075 of these with cancer), presenting with symptomatic VTE in the previous three months and enrolled in the worldwide RIETE registry, were evaluated to assess overall and pulmonary embolism (PE)-related mortality, and their potential predictors, with particular focus on patients with cancer.Overall 3-month mortality in the total RIETE population was 7.9%, and death was considered PE-related in 1.4%. Significantly more patients died among those with cancer (26.4%, vs 4.1% in no-cancer group, p