Hagfish (Cyclostomata, Vertebrata): searching for the ancestral developmental plan of vertebrates
Hagfish (Cyclostomata, Vertebrata): searching for the ancestral developmental plan of vertebrates
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DOI：
10.1002/bies.20701
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发表时间：
2008-02-01
期刊：
影响因子：
4
通讯作者：
Ota, Kinya G.
中科院分区：
文献类型：
--
作者：
Kuratani, Shigeru;Ota, Kinya G.
盲鳗的系统发育位置仍然是个谜。相反，分子数据表明单系的圆口动物，几个形态特征意味着更古老的状态，这种动物相比，七鳃鳗。要解决这个问题，需要对盲鳗的胚胎学，特别是神经嵴的了解。盲鳗的早期发育一直是个谜。我们收集了一种浅水栖息的盲鳗，Eptatretus burgeri，建立了一个水族箱，旨在模拟其栖息地，并成功地获得了几个胚胎。通过观察已知在神经嵴中发挥基本作用的基因的组织学和表达，我们发现盲鳗嵴像其他脊椎动物一样以分层迁移细胞的形式发育。我们的结论是，分层的神经嵴是脊椎动物的突触，似乎已经出现在他们的进化史的开始，之前的分离出的盲鳗血统。
The phylogenetic position of the hagfish remains enigmatic. In contrast to molecular data that suggest monophyly of the cyclostomes, several morphological features imply a more ancestral state of this animal compared with the lampreys. To resolve this question requires an understanding of the embryology of the hagfish, especially of the neural crest. The early development of the hagfish has long remained a mystery. We collected a shallow-water-dwelling hagfish, Eptatretus burgeri, set up an aquarium tank designed to resemble its habitat, and successfully obtained several embryos. By observing the histology and expression of genes known to play fundamental roles in the neural crest, we found that the hagfish crest develops as delaminating migratory cells, as in other vertebrates. We conclude that the delaminating neural crest is a vertebrate synapomorphy that seems to have appeared from the beginning of their evolutionary history, before the splitting away of the hagfish lineage.