Transcranial magnetic stimulation: studying the brain-behaviour relationship by induction of 'virtual lesions'

Transcranial magnetic stimulation: studying the brain-behaviour relationship by induction of 'virtual lesions'
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DOI:
10.1098/rstb.1999.0476
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发表时间:
1999-07-29
影响因子:
6.3
通讯作者:
Keenan, JP
Keenan, JP
中科院分区:
生物学1区
文献类型:
--
作者:
Pascual-Leone, A;Bartres-Faz, D;Keenan, JP

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经颅磁刺激(TMS)提供了一种非侵入性的方法,在大脑中诱导局灶电流并对目标皮层的功能进行短暂调制。尽管对焦点和作用机制的了解有限,但经颅磁刺激为研究正常人的大脑行为关系提供了一个独特的机会。经颅磁刺激可以通过建立大脑活动和任务表现之间的因果关系以及探索大脑功能连接来增强其他神经成像技术的结果。
Transcranial magnetic stimulation (TMS) provides a non-invasive method of induction of a focal current in the brain and transient modulation of the function of the targeted cortex. Despite limited understanding about focality and mechanisms of action, TMS provides a unique opportunity of studying brain-behaviour relations in normal humans. TMS can enhance the results of other neuroimaging techniques by establishing the causal link between brain activity and task performance, and by exploring functional brain connectivity.