Current theories on the cause of Parkinson's disease.
Current theories on the cause of Parkinson's disease.
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关于帕金森病病因的最新理论。
DOI：
10.1136/jnnp.52.suppl.13
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Langston,JW
中科院分区：
文献类型：
--
作者：
Langston,JW
在这篇文章中，我将尝试描绘导致帕金森病的事件序列的当前理论的有点令人生畏的任务。任何这种性质的审查都必须以讨论疾病的原因为边界，当然，这仍然是未知的。尽管如此，随着我们对黑质纹状体系统的了解越来越多，无论是在正常情况下还是在疾病中，似乎是时候把一些碎片放在一起，试图缩小最终可能导致我们所知的帕金森病的因素。
In this article, I will attempt the somewhat daunting task of delineating current theories on the sequence of events that lead to Parkinson's disease. Any review of this nature must border on a discussion of the cause of the disease which, of course, remains unknown. Nonetheless, with our increasing knowledge about the nigrostriatal system, both in normality and disease, it seems that the time is right to put some of the pieces together in an attempt to narrow down the factors that might eventually lead to what we know as Parkinson's disease.