Towards a definition of sarcopenia - results from epidemiologic studies
Towards a definition of sarcopenia - results from epidemiologic studies
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DOI：
10.1007/s12603-009-0202-y
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发表时间：
2009-08-01
影响因子：
5.8
通讯作者：
Visser, M.
中科院分区：
文献类型：
--
作者：
Visser, M.
与年龄相关的肌肉量减少，也称为肌肉减少症，在衰老研究中受到越来越多的关注。虽然该概念经常用于研究环境并引入临床环境，但迄今尚未就其定义达成共识。本文概述了迄今为止文献中提出的肌少症定义的历史。它将描述在大型流行病学研究中用于开发低肌肉质量（或力量）切点的方法，基于这些切点的肌肉减少症如何与功能结果相关，以及不同定义的优缺点。这一综述将有助于目前需要制定一个一致的肌少症定义，可用于所有相关设置。
The age-related loss of muscle mass, also called sarcopenia, is receiving increasing attention in aging research. While the concept is frequently being used in research settings and introduced to clinical settings, thus far no consensus on its definition has been established. This article provides an overview of the history of sarcopenia definitions proposed in the literature thus far. It will describe the methodology used to develop the cutpoints for low muscle mass (or strength) in large epidemiological studies, how sarcopenia based on these cutpoints relates to functional outcomes, and the advantages and disadvantages of the different definitions. This overview will contribute to the current need to develop a consensus definition of sarcopenia which can be used in all relevant settings.