A nitroxyl-responsive near-infrared fluorescent chemosensor for visualizing H2S/NO crosstalk in biological systems
A nitroxyl-responsive near-infrared fluorescent chemosensor for visualizing H2S/NO crosstalk in biological systems
复制标题
用于可视化生物系统中 H2S/NO 串扰的硝酰基响应性近红外荧光化学传感器
DOI：
10.1039/c9cc04060a
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发表时间：
2019
影响因子：
4.9
通讯作者：
Peng Xiaojun
中科院分区：
文献类型：
--
作者：
Yang Mingwang;Fan Jiangli;Sun Wen;Du Jianjun;Long Saran;Shao Kun;Peng Xiaojun
我们提出了一种近红外(NIR)荧光探针NR-HNO，它通过对活细胞和组织中氮氧基的快速响应(5min)和大的斯托克斯位移(131 Nm)的荧光检测，成功地显示了H_2S/NO的“串扰”，并用于活体小鼠的氮氧基成像。
We present a near-infrared (NIR) fluorescent probe, NR-HNO, which was successfully applied to visualizing H2S/NO “crosstalk” by the fluorescence detection of nitroxyl with a fast response time (5 min) and a large Stokes shift (131 nm) in living cells and tissue; it was also used to image nitroxyl in live mice.