MicroRNA‐491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition

MicroRNA‐491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition
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DOI:
10.1111/liv.12190
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发表时间:
2013-09
影响因子:
6.7
通讯作者:
Yun Zhou;Yuan Li;Jingwen Ye;Rongrong Jiang;Hangyi Yan;Xiaojun Yang;Qizhan Liu;Jianping Zhang
Yun Zhou;Yuan Li;Jingwen Ye;Rongrong Jiang;Hangyi Yan;Xiaojun Yang;Qizhan Liu;Jianping Zhang
中科院分区:
医学2区
文献类型:
--
作者:
Yun Zhou;Yuan Li;Jingwen Ye;Rongrong Jiang;Hangyi Yan;Xiaojun Yang;Qizhan Liu;Jianping Zhang

文献摘要

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肝细胞癌(HCC)是全球范围内第三大癌症相关死亡原因;由于肝内外转移和术后复发,HCC患者的预后仍然很差。本研究的目的是确定肝癌转移的分子机制。
Hepatocellular carcinoma (HCC) is the third leading cause of cancer‐related mortality worldwide; the prognosis of HCC patient remains poor owing to intrahepatic and extrahepatic metastasis and postsurgical recurrence. The aim of the present study is to determine the molecular mechanisms underlying the metastasis of HCC.