TARICHATOXIN - ISOLATION AND PURIFICATION
TARICHATOXIN - ISOLATION AND PURIFICATION
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DOI：
10.1126/science.140.3564.295
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发表时间：
1963-01-01
期刊：
影响因子：
56.9
通讯作者：
MOSHER, HS
中科院分区：
文献类型：
--
作者：
BROWN, MS;MOSHER, HS
在加利福尼亚蝾螈（Taricha torosa）的胚胎中产生的强效神经毒素以晶体形式获得。对于一只20克重的小鼠，它的致死皮下剂量约为0.14 [mu]g，与蛤蚌毒素和河豚毒素一起，是已知毒性最大的非蛋白物质之一。
The potent neurotoxin occurring in the embryos of the California newt, Taricha torosa, was obtained in crystalline form. With a lethal subcutaneous dose of approximately 0.14 [mu]g for a 20-g mouse, it is, along with saxitoxin and tetrodotoxin, one of the most toxic nonprotein substances known.