Reconstructing historical exposures to elongate mineral particles (EMPs) in the taconite mining industry for 1955-2010.
Reconstructing historical exposures to elongate mineral particles (EMPs) in the taconite mining industry for 1955-2010.
复制标题
重建 1955-2010 年铁燧岩采矿业中细长矿物颗粒 (EMP) 的历史暴露。
DOI：
10.1080/15459624.2019.1676431
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发表时间：
2019
影响因子：
2
通讯作者：
Ramachandran,Gurumurthy
中科院分区：
文献类型：
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作者：
Shao,Yuan;Hwang,Jooyeon;Alexander,BruceH;Mandel,JeffreyH;MacLehose,RichardF;Ramachandran,Gurumurthy
作为正在进行的流行病学研究的一部分，以评估接触塔康作业粉尘与呼吸道疾病的发展之间的关系，这项研究的目标是重建1955-2010年间明尼苏达州塔肯采矿业工人接触细长矿物颗粒(EMP)的情况。历史的NIOSH-7400和等效的EMP个人暴露数据来自两个来源：(1)矿山安全和健康管理局(MSHA)在线数据库，记录了1978年以来的所有检查结果，其中包括与本研究相关的13个MSHA矿山ID从1978年到2010年的655个EMP监测记录；以及(2)矿业公司的内部监测报告包含96个个人EMP暴露记录。2010年，通过获得1,285份个人样本，对所有活跃矿井中不同工作岗位的工人进行了NIOSH-7400电磁脉冲个人暴露测量。经过数据处理后，将所有数据归入7个矿山、8个部门。在每个矿山部门内，使用两种方法预测了每一年的年度电磁脉冲平均浓度，单位为f/cc。两种方法的表现因情况而异。本文中描述的每种方法所依据的假设都有局限性。根据有限的历史测量和2010-2011年进行的线性回归(方法1)得不到合理和可信的斜率值。方法2假定同一部门的EMP和呼吸性粉尘具有相同的历史时间趋势。这种方法使我们能够利用历史可吸入粉尘数据集更合理的斜率估计，并为大多数地点产生更可信的历史暴露估计。这项工作使用了两种不同的工作暴露矩阵(JEM)，为研究暴露评估对流行病学结果的潜在影响提供了一个独特的研究机会。在流行病学研究中，这两种JEM都被用来评估电磁脉冲与呼吸系统疾病之间的关系。
As part of ongoing epidemiological studies for assessing the association between exposure to dust from taconite operations and the development of respiratory diseases, the goal of this study was to reconstruct the exposures of workers to elongate mineral particle (EMP) in the Minnesota taconite mining industry from 1955–2010. Historical NIOSH-7400 and equivalent EMP personal exposure data were extracted from two sources: (1) the Mine Safety and Health Administration (MSHA) online database recorded for all inspection results since 1978 with 655 EMP monitoring records from 1978–2010 for 13 MSHA Mine IDs associated with this study; and (2) the mining companies’ internal monitoring reports contained 96 personal EMP exposure records. NIOSH-7400 EMP personal exposures were measured for workers in different jobs in all active mines in 2010 by obtaining 1,285 personal samples. After data treatment, all data were grouped into seven mines and eight departments. Within each mine-department, the yearly EMP mean concentration in f/cc for each year of operation was predicted using two approaches. The performance of two approaches varied by situation. The assumptions underlying each approach described in this article have limitations. A linear regression based on limited historical measurements and those made in 2010–2011 (Approach 1) does not yield reasonable and plausible values of the slope. Approach 2 assumes that the EMP and the respirable dust in the same department share the same historical time trend. This approach allowed us to avail of the more reasonable slope estimates from the historical respirable dust data set and yielded more plausible historical exposure estimates for most locations. This work with two different job exposure matrix (JEMs) provides a unique research opportunity to study the potential impact of exposure assessment to epidemiological results. Both JEMs are being used to assess associations between EMP and respiratory disease in epidemiological studies.