Arthritis and Risk of Cognitive and Functional Impairment in Older Mexican Adults.
Arthritis and Risk of Cognitive and Functional Impairment in Older Mexican Adults.
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墨西哥老年人的关节炎和认知和功能障碍的风险。
DOI：
10.1177/0898264316636838
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发表时间：
2017-04
影响因子：
2.8
通讯作者：
Wong R
中科院分区：
文献类型：
--
作者：
Veeranki SP;Downer B;Jupiter D;Wong R
这项研究调查了诊断为关节炎的墨西哥老年人认知和功能障碍的风险。参与者包括2,681名墨西哥人，年龄≥60岁，参加了墨西哥健康与老龄化研究队列。参与者被分为关节炎组和无关节炎组。主要结果包括被分为“认知受损”组和“认知正常”组的参与者。次要结果包括被分为正常组、仅功能受损组、仅认知受损组或痴呆组（包括认知和功能受损组）。采用多变量逻辑模型和多项回归模型来评估两者之间的关系。总的来说，16%或7%的人被诊断为认知障碍或痴呆症。与没有关节炎的墨西哥老年人相比，那些被诊断患有关节炎的人患功能障碍的风险显著增加（调整优势比[OR] 1.82, 95%可信区间[CI] =[1.45, 2.29]），但痴呆的风险没有增加。在墨西哥老年人中，关节炎与功能损伤风险增加有关，但与11岁后的痴呆无关。
This study investigated the risk of cognitive and functional impairment in older Mexicans diagnosed with arthritis. Participants included 2,681 Mexicans, aged ≥60 years, enrolled in the Mexican Health and Aging Study cohort. Participants were categorized into arthritis and no arthritis exposure groups. Primary outcome included participants categorized into “cognitively impaired” or “cognitively normal” groups. Secondary outcomes included participants categorized into Normal, Functionally Impaired only, Cognitively Impaired only, or Dementia (both cognitively and functionally impaired) groups. Multivariable logistic and multinomial regression models were used to assess the relationships. Overall, 16% or 7% were diagnosed with cognitive impairment or dementia. Compared with older Mexicans without arthritis, those who were diagnosed with arthritis had significantly increased risk of functional impairment (adjusted odds ratio [OR] 1.82, 95% confidence interval [CI] = [1.45, 2.29]), but not of dementia. Arthritis is associated with increased risk of functional impairment, but not with dementia after 11 years in older Mexicans.
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影响因子：
3.9
作者：
Cunningham C
通讯作者：
Cunningham C
影响因子：
9.9
作者：
BREITNER, JCS;GAU, BA;ANTHONY, JC
通讯作者：
ANTHONY, JC
影响因子：
12.4
作者：
Ayres, JG;Higgins, B;Fox, H
通讯作者：
Fox, H
DOI：
10.1089/jamp.2010.0827
发表时间：
2010-12-01
影响因子：
3.4
作者：
Abuan, Tammy;Yeager, Melissa;Montgomery, A. Bruce
通讯作者：
Montgomery, A. Bruce
影响因子：
8.3
作者：
Chen LY;Lopez FL;Gottesman RF;Huxley RR;Agarwal SK;Loehr L;Mosley T;Alonso A
通讯作者：
Alonso A