Evaluation of intracavitary ultrasound arrays for hyperthermia
Evaluation of intracavitary ultrasound arrays for hyperthermia
复制标题
腔内超声阵列热疗评估
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
K. Hynynen
中科院分区：
文献类型：
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作者：
C. Diederich;I.M. Duponchelle;M. Buchanan;K. Hynynen
通过体外（酒精固定）和体内（靠近直肠壁）狗肾加热实验验证了腔内超声热疗的可行性。体外和体内结果均表明，即使对于高度灌注的器官，非聚焦阵列也能有效地输送能量至2-3 cm深，并控制能量沿阵列长度沿着沉积。循环水温度可用于将最高温度的深度推至离直肠壁超过1 cm，即使在灌注的肾脏中。正如预期的那样，灌注倾向于保持该最大值更接近表面，并降低灌注区域中温度的总体升高。初步结果表明，腔内相控阵是可行的。<<ETX>>
The feasibility of intracavitary ultrasound hyperthermia was verified experimentally by heating in vitro (alcohol fixed) and in vivo (relocated next to the rectal wall) dog kidneys. Both in vitro and in vivo results showed that, even for a highly perfused organ, the nonfocused arrays effectively deliver energy up to 2-3 cm deep with control over the energy deposition along the length of the array. The circulating water temperature can be used to push the depth of the maximum temperature over 1 cm from the rectal wall, even in a perfused kidney. As expected, perfusion tends to keep this maximum closer to the surface and decreases the overall rise in temperature in the perfused regions. Initial results indicate that intracavitary phased arrays are feasible.<<ETX>>