A METHOD FOR ASSESSING DRUG-THERAPY APPROPRIATENESS
A METHOD FOR ASSESSING DRUG-THERAPY APPROPRIATENESS
复制标题
DOI：
10.1016/0895-4356(92)90144-c
复制
发表时间：
1992-10-01
影响因子：
7.2
通讯作者：
FEUSSNER, JR
中科院分区：
文献类型：
--
作者：
HANLON, JT;SCHMADER, KE;FEUSSNER, JR
本研究评估了一种新的药物适当性指数的可靠性。使用该指数，独立的评估，由10个门诊，老年男性患者的临床药剂师和内科老年病学家采取的慢性药物。他们的总体评价者间一致性为药物适当性（ppos）为0.88，药物不适当性（pneg）为0.95;总体kappa为0.83。他们的评分者内一致性为ppos总体为0.94，pneg总体为0.98，而总体kappa为0.92。由两名不同的临床药师对10名不同的老年男性门诊患者的慢性药物进行独立评估。他们的总体评分者间一致性为ppos为0.76，pneg为0.93，而总体kappa为0.59。这一新的指标提供了一种可靠的方法来评估药物治疗的适当性。它的使用可能适用于医疗服务研究和机构质量保证计划中的护理结果测量质量。
This study evaluated the reliability of a new medication appropriateness index. Using the index, independent assessments were made of chronic medications taken by 10 ambulatory, elderly male patients by a clinical pharmacist and an internist-geriatrician. Their overall inter-rater agreement for medication appropriateness (ppos) was 0.88, and for medication inappropriateness (pneg) was 0.95; the overall kappa was 0.83. Their intra-rater agreement for ppos was 0.94 overall, for pneg was 0.98 overall while the overall kappa was 0.92. The chronic medications taken by 10 different ambulatory elderly male patients were independently evaluated by two different clinical pharmacists. Their overall inter-rater agreement for ppos was 0.76, and for pneg was 0.93, while the overall kappa was 0.59. This new index provides a reliable method to assess drug therapy appropriateness. Its use may be applicable as a quality of care outcome measure in health services research and in institutional quality assurance programs.