A critical review of the major indicators of prognosis after resection of hepatic metastases from colorectal carcinoma.

A critical review of the major indicators of prognosis after resection of hepatic metastases from colorectal carcinoma.
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DOI:
10.1016/s1055-3207(02)00091-1
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发表时间:
2003-01-01
影响因子:
1.9
通讯作者:
Scheele, Johannes
Scheele, Johannes
中科院分区:
医学4区
文献类型:
--
作者:
Altendorf-Hofmann, Annelore;Scheele, Johannes

文献摘要

被引文献

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转移性结直肠癌的肝切除术已经急剧增加,并且有明确的证据表明这种手术的有效性。然而,关于适当的患者选择、肝切除的范围和时间以及辅助或替代治疗选择的争议仍然存在。本文回顾了作者600多例肝切除术的经验,并讨论了有关文献。结果强调了肉眼和组织学上完全清除肿瘤的重要性,即所谓的“R0切除”。"
Hepatic resections for metastatic colorectal cancer have dramatically increased, and there is clear evidence of the effectiveness of this type of surgery. Controversy, however, persists regarding appropriate patient selection, extent and timing of liver resection, and adjuvant or alternative therapeutic options. This article reviews the authors' experience with more than 600 hepatic resections and the relevant literature is discussed. The results underscore the importance of macroscopically and histologically complete tumor clearance, a so-called "R0 resection."