Psychiatric disorders in temporal lobe epilepsy: An overview from a tertiary service in Brazil
Psychiatric disorders in temporal lobe epilepsy: An overview from a tertiary service in Brazil
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DOI：
10.1016/j.seizure.2010.07.004
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发表时间：
2010-10-01
影响因子：
3
通讯作者：
Teixeira, Antonio Lucio
中科院分区：
文献类型：
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作者：
de Oliveira, Guilherme Nogueira M.;Kummer, Arthur;Teixeira, Antonio Lucio
目的：为了评估的频率和强度的精神障碍在一组颞叶癫痫（TLE）患者从三级保健center.Methods：临床和社会人口学数据的73例患者进行了收集和神经精神评估与以下仪器：简易精神状态检查（MMSE），结构化临床访谈采用MINI-PLUS量表、汉密尔顿焦虑量表（HAM-A）、汉密尔顿抑郁量表（HAM-D）、简明精神病评定量表（BPRS）进行评定。TLE患者一生中出现精神疾病的频率很高（70%），最常见的是情绪障碍（49.3%）。在评估时，27.4%的患者患有抑郁症，9.6%的患者符合双相情感障碍的标准。然而，抑郁症没有得到适当的诊断和治疗。焦虑障碍也很常见（42.5%），主要是广泛性焦虑障碍（GAD）（21.9%）。强迫症（OCD）是目前在11.0%和精神病性障碍的样本中的5.5%。左内侧颞叶硬化症（LMTS）患者表现出更多的精神病理学特征，主要是焦虑症（p = 0.006），并且HAM-A和HAM-D评分较高（p
Purpose: To evaluate the frequency and intensity of psychiatric disorders in a group of temporal lobe epilepsy (TLE) patients from a tertiary-care center.Methods: Clinical and sociodemographic data of 73 patients were collected and a neuropsychiatric evaluation was performed with the following instruments: Mini-Mental State Examination (MMSE), structured clinical interview (MINI-PLUS), Hamilton Anxiety Scale (HAM-A), Hamilton Depression Scale (HAM-D), Brief Psychiatric Rating Scale (BPRS).Results: Patients with TLE showed a high frequency of lifetime psychiatric disorders (70%), the most frequent being mood disorders (49.3%). At assessment, 27.4% of the patients were depressed and 9.6% met criteria for bipolar disorder. Nevertheless, depression had not been properly diagnosed nor treated. Anxiety disorders were also frequent (42.5%), mainly generalized anxiety disorder (GAD) (21.9%). Obsessive compulsive disorder (OCD) was present in 11.0% and psychotic disorders in 5.5% of the sample. Patients with left mesial temporal sclerosis (LMTS) exhibited more psychopathologic features, mainly anxiety disorders (p = 0.006), and scored higher on HAM-A and HAM-D (p