Salivary and oral components of Sjögren's syndrome.
Salivary and oral components of Sjögren's syndrome.
复制标题
干燥综合征的唾液和口腔成分。
DOI：
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发表时间：
1992
影响因子：
2.3
通讯作者：
P. Fox
中科院分区：
文献类型：
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作者：
T. Daniels;P. Fox
SS的口内症状和体征不是SS特有的，与唾液功能减弱的其他疾病共有。唾液减少会导致慢性口腔不适和功能问题，并使患者容易患龋齿和口腔念珠菌病。许多方法已被用来评估SG在SS客观，但目前唇唾液腺活检标本显示局灶性淋巴细胞性涎腺炎提供了最好的诊断标准SS的唾液成分，在其疾病的特异性，方便，可用性和低风险。SS患者口干症的治疗包括：（1）通过频繁和定期局部应用氟化物、仔细的牙科监督以及避免在两餐之间使用蔗糖和其他可代谢的碳水化合物来预防新发和复发性龋齿;（2）通过诊断和治疗口腔念珠菌病来减轻口腔症状（必要时重复）;和（3）尝试通过用生理性促涎剂或毛果芸香碱刺激唾液分泌来替代失去的唾液，或者如果不能刺激足够量的唾液，则使用某种形式的唾液替代物，特别是对于戴全口义齿的患者。
The intraoral symptoms and signs of SS are not specific to SS, being shared with other conditions in which salivary function is diminished. The decrease in saliva causes chronic oral discomfort and functional problems and predisposes patients to dental caries and oral candidiasis. Many methods have been used to assess SGs in SS objectively, but at present a labial salivary gland biopsy specimen showing focal lymphocytic sialadenitis provides the best diagnostic criterion for the salivary component of SS, in terms of its disease specificity, convenience, availability, and low risk. The treatment of xerostomia in patients with SS consists of (1) preventing new and recurrent dental caries by frequent and regular application of topical fluoride, careful dental supervision, and avoidance of sucrose and other metabolizable carbohydrates between meals; (2) reducing oral symptoms by diagnosing and treating oral candidiasis (repeatedly if necessary); and (3) attempting to replace lost saliva by stimulating salivary secretion with physiologic sialogogues or pilocarpine, or if adequate amounts of saliva cannot be stimulated, using some form of saliva substitute, especially for patients wearing complete dentures.