Soybean Lectin Agglutination and E-Rosette Depletion for Removal of T-Cells from HLA-Identical Marrow Grafts: Results in 60 Consecutive Patients Transplanted for Hematologic Malignancy

Soybean Lectin Agglutination and E-Rosette Depletion for Removal of T-Cells from HLA-Identical Marrow Grafts: Results in 60 Consecutive Patients Transplanted for Hematologic Malignancy
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大豆凝集素和 E-Rosette 去除从 HLA 相同骨髓移植物中去除 T 细胞:60 名连续接受血液恶性肿瘤移植的患者的结果

DOI:
10.1007/978-94-009-4273-8_31
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发表时间:
1986
期刊:
影响因子:
6
通讯作者:
B. Shank
B. Shank
中科院分区:
生物学2区
文献类型:
--
作者:
R. O'reilly;N. Collins;J. Brochstein;N. Kernan;C. Keever;H. Castro;N. Flomenberg;J. Laver;S. Gulati;J. Burns;D. Emanual;C. Bordignon;T. Small;D. Hornick;B. Kushner;B. Shank

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移植物抗宿主病(GvHD)是白血病同种hla骨髓移植成功的主要障碍。大约60%接受同种hla骨髓移植的患者会发展为GvHD。严重(3-4级)GvHD与高早期死亡率相关(bb0 - 75%)。这种形式的移植物抗宿主病在成人中尤为常见,并导致该年龄组移植后的高急性死亡率(1)。
Graft vs host disease (GvHD) constitutes a major obstacle to the success of HLA-identical marrow transplants for leukemia. Approximately 60% of patients receiving HLA-identical marrow grafts will develop GvHD. Severe (Grade 3–4) GvHD is associated with a high early mortality (>75%). Such forms of GvHD are particularly common among adults, and contribute to the high acute mortality observed following transplants in this age group (1).
通过大豆凝集素和绵羊红细胞分离的 HLA-A、B、D、DR 不相容亲代骨髓细胞的严重联合免疫缺陷的移植。
DOI: --
发表时间: 1983
期刊: Blood
影响因子: 20.3
作者:
Reisner,Y;Kapoor,N;Kirkpatrick,D;Pollack,MS;Cunningham-Rundles,S;Dupont,B;Hodes,MZ;Good,RA;O'Reilly,RJ
通讯作者: O'Reilly,RJ
同种异体骨髓移植:现状和未来方向。
DOI: --
发表时间: 1983
期刊: Blood
影响因子: 20.3
作者:
O'Reilly,RJ
通讯作者: O'Reilly,RJ