Acalculous Acute Pancreatitis in a COVID-19 Patient.
Acalculous Acute Pancreatitis in a COVID-19 Patient.
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DOI：
10.12890/2020_001710
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发表时间：
2020-01-01
影响因子：
--
通讯作者：
Alvoeiro, Lourdes
中科院分区：
文献类型：
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作者：
Meireles, Pedro Antunes;Bessa, Filipe;Alvoeiro, Lourdes
2019年冠状病毒病(新冠肺炎)是由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的一种多系统疾病，表现从轻微的上呼吸道症状到引起急性呼吸窘迫综合征的细胞因子风暴。胰腺外分泌组织和内分泌岛都表达血管紧张素转换酶2(ACE2)，这是已证实的SARS-CoV-2细胞内化的受体。在新冠肺炎患者中，胰酶的增加已被越来越多地认识到，但对这一人群中急性胰腺炎的真实流行情况知之甚少。我们报告了一例新冠肺炎患者并发急性非结石性胰腺炎的病例。报道要点：急性胰腺炎可能是SARS-CoV-2感染的表现。未来的研究必须解决新冠肺炎患者胰腺受累的真正影响。
Coronavirus disease 2019 (COVID-19) is a multisystemic condition caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with manifestations ranging from mild upper respiratory symptoms to cytokine storm causing acute respiratory distress syndrome. Pancreatic exocrine tissue and endocrine islets both express angiotensin-converting enzyme 2 (ACE2), the proven receptor for SARS-CoV-2 cell internalization. An increase in pancreatic enzymes has been increasingly recognized in patients with COVID-19, but little is known about the real prevalence of acute pancreatitis in this population. We report a case of acute acalculous pancreatitis in a COVID-19 patient.LEARNING POINTS: Acute pancreatitis may be a manifestation of SARS-CoV-2 infection.Future studies must address the real impact of pancreatic involvement in COVID-19 patients.