Postoperative management of local colorectal cancer: therapy and surveillance.
Postoperative management of local colorectal cancer: therapy and surveillance.
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局部结直肠癌的术后管理：治疗和监测。
DOI：
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
S. Waldman
中科院分区：
文献类型：
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作者：
D. Weinberg;R. Desnoyers;A. Gelmann;B. Boman;S. Waldman
辅助治疗被广泛推荐用于III期结肠癌和II、III期直肠癌。虽然以氟尿嘧啶为基础的方案是标准的，但新的药物单独或联合使用可能会提高反应率。尽管几乎所有患者在手术切除后都进入了术后监测计划，但这种监测的临床有效性尚不规范，值得怀疑。对这些项目的不同组成部分（实验室、放射照相和内窥镜）的使用进行的批判性审查发现，对强化监测的支持很少。
Adjuvant therapy is widely recommended for stage III colon cancer and stages II and III rectal cancer. Although fluorouracil-based regimens are standard, newer agents either alone or in combination may improve response rates. Although nearly all patients enter a postoperative surveillance program after surgical resection, the clinical effectiveness of such surveillance, which is not standardized, is questionable. Critical review of the use of different components (laboratory, radiographic, and endoscopic) of these programs finds little support for intensive surveillance.