Pan Vascular Medicine

Pan Vascular Medicine
复制标题

泛血管医学

DOI:
--
复制
发表时间:
2002
期刊:
Springer Berlin Heidelberg
影响因子:
--
通讯作者:
E. Topol
E. Topol
中科院分区:
--
文献类型:
--
作者:
P. Lanzer;E. Topol

文献摘要

参考文献

被引文献

相似文献

10-13个谷氨酸残基的γ-氢离子,靠近新生前原蛋白的NH 2-末端。这留下碳负离子,其被游离CO2攻击形成γ-羧基谷氨酸。从这串Gla残基引出的负电荷有助于与Ca+的结合和产生适当的构象以结合阴离子磷脂膜[46,47]。抗凝治疗的一个重要目标是还原性氢化物的再生所需的过程。
ion of the y-hydrogen of 10-13 glutamate residues, near the NH2-terminal end of the nascent preproprotein. This leaves a carbanion that is attacked by free C02 forming y-carboxyglutamic acid. The negative charge elicited from this string of Gla residues contributes to the binding to ca>+ and the generation of the appropriate conformation to bind to anionic phospholipid membrane [46, 47]. One important target for anticoagulant therapy is the process required for the regeneration of reduced hydro-
DOI: --
发表时间: 1995-09
期刊: Circulation
影响因子: 37.8
作者:
P. Shah;E. Falk;J. Badimón;A. Fernández-Ortiz;A. Mailhac;G. Villareal-Levy;J. Fallon;J. Regnstrom;V. Fuster
通讯作者: P. Shah;E. Falk;J. Badimón;A. Fernández-Ortiz;A. Mailhac;G. Villareal-Levy;J. Fallon;J. Regnstrom;V. Fuster
DOI: 10.1161/01.res.71.4.850
发表时间: 1992-10-01
影响因子: 20.1
作者:
LOREE, HM;KAMM, RD;LEE, RT
通讯作者: LEE, RT