Cryopreservation has no effect on meiotic recombination and synapsis in testicular tissues
Cryopreservation has no effect on meiotic recombination and synapsis in testicular tissues
复制标题
冷冻保存对睾丸组织的减数分裂重组和突触没有影响
DOI：
10.1016/j.fertnstert.2008.04.074
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发表时间：
2009-04-01
影响因子：
6.7
通讯作者：
Shi, Qinghua
中科院分区：
文献类型：
--
作者：
Li, Jianhua;Leng, Mei;Shi, Qinghua
通过比较来自同一男性的冷冻和新鲜睾丸组织的上述参数，评估冷冻保存对睾丸组织减数分裂进展、联会、重组和联会复合体（SC）结构的影响。在新鲜和冷冻睾丸组织之间，减数分裂进展、每个细胞的 MLH1 灶的平均数量、具有不同 MLH1 灶数量的常染色体 SC 的平均数量或突触的保真度没有观察到差异。 （Fertil Steril (R) 2009；91:1404-7。(C) 2009，美国生殖医学会。）
The effects of cryopreservation on meiotic progression, synapsis, recombination, and structure of synaptonemal complexes (SCs) in testicular tissues were evaluated by comparing the above-mentioned parameters in frozen and fresh testicular tissues from the same men. No differences in meiotic progression, the mean number of MLH1 foci per cell, the mean number of autosomal SCs with different numbers of MLH1 foci, or the fidelity of the synapsis were observed between fresh and frozen testicular tissues. (Fertil Steril (R) 2009;91:1404-7. (C) 2009 by American Society for Reproductive Medicine.)