Observations on Histamine and Histaminolysis in Pregnancy.1

Observations on Histamine and Histaminolysis in Pregnancy.1
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妊娠期组胺和组织胺溶解的观察1

DOI:
10.1111/j.1748-1716.1949.tb00586.x
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发表时间:
1949
期刊:
Acta Physiologica Scandinavica
影响因子:
--
通讯作者:
F. Wicksell
F. Wicksell
中科院分区:
--
文献类型:
--
作者:
F. Wicksell

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Summary. 1  No changes were found to take place in the histamine content of plasma or urine during parturition. In agreernent with earlier investigators urine was found to contain histamine in a free form and also in a conjugated form, from which it can be liberated through acid hydrolysis. 2  The histarninolytic activity of placenta is very high. Inspite of this histamine is present in this organ. Contrary to what is thecase in maternal plasma the histaminolytic power of foetal plasma is low. No decrease in the histamine c, ontent takes place when foetal plasma flows through the placenta. The histamine content of maternal and foetal plasma is of the same order. Histamine seems t o be present in the plasma in a form which is ultrafilterable but not attacked by the histaminase. 3  The size of the flare of the triple response caused by intra-dermal injections of histamine is of the same order in pregnant and non-pregnant women.