Adherence to asthma management guidelines by middle-aged adults with current asthma
Adherence to asthma management guidelines by middle-aged adults with current asthma
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DOI：
10.1136/thx.2009.118430
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发表时间：
2009-12-01
期刊：
影响因子：
10
通讯作者：
Walters, E. H.
中科院分区：
文献类型：
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作者：
Kandane-Rathnayake, R. K.;Matheson, M. C.;Walters, E. H.
背景：随着全球范围内哮喘负担的增加，已经做出了大量努力来制定和更新管理指南。使用塔斯马尼亚纵向健康研究（TAHS）的数据，充分的哮喘管理中年成人哮喘investigated.Methods：有关肺功能测定，用药史和目前的哮喘状态的信息收集了最近的TAHS时，参与者在他们的40多岁。只有那些报告曾患有哮喘的人才有资格进行分析。结果：在702名报告曾患有哮喘的参与者中，50%目前患有哮喘（n=351），其中71%被归类为持续性哮喘（n=98轻度，n=92中度，n=58严重）。大多数（85.2%）目前患有哮喘的参与者在过去12个月内使用了某种形式的哮喘药物，但使用最低限度的适当预防药物的比例很低（26%）。后支气管扩张剂气流阻塞逐渐增加，从轻度到严重的持续性哮喘的管理不足，但没有为那些在适当的therapeutic.Conclusion：适当使用哮喘药物治疗的中年组的成人目前哮喘是不够的，特别是对于那些成年发病的中度或重度持续性疾病，没有哮喘家族史。这些结果表明，正确使用预防药物可以防止与严重程度增加相关的肺功能进行性下降。这不仅意味着生活质量差，而且还意味着固定气流阻塞的发展。
Background: With the increasing burden of asthma worldwide, much effort has been given to developing and updating management guidelines. Using data from the Tasmanian Longitudinal Health Study (TAHS), the adequacy of asthma management for middle-aged adults with asthma was investigated.Methods: Information about spirometry, medication history and current asthma status was collected by the most recent TAHS when participants were in their mid 40s. Only those who reported ever having asthma were eligible for analysis.Results: Of the 702 participants who reported ever having asthma, 50% had current asthma (n=351) of whom 71% were categorised as having persistent asthma (n=98 mild, n=92 moderate, n=58 severe). The majority (85.2%) of participants with current asthma had used some form of asthma medication in the past 12 months, but the proportion of the use of minimally adequate preventer medication was low (26%). Post-bronchodilator airflow obstruction increased progressively from mild to severe persistent asthma for those inadequately managed, but not for those on adequate therapy.Conclusion: Appropriate use of asthma medication by this middle-aged group of adults with current asthma was inadequate, especially for those with adult-onset moderate or severe persistent disease and without a family history of asthma. These results suggest that proper use of preventer medication could protect against the progressive decline in lung function associated with increasing severity. This has implications not just for poor quality of life, but also for the development of fixed airflow obstruction.