Synthesis and Surface Properties of Fluorocarbon End-Capped Biodegradable Polyesters
Synthesis and Surface Properties of Fluorocarbon End-Capped Biodegradable Polyesters
复制标题
氟碳封端生物降解聚酯的合成及表面性能
DOI：
10.1021/ma0000327
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发表时间：
2001
期刊：
影响因子：
5.5
通讯作者：
W. Hicks
中科院分区：
文献类型：
--
作者：
Won‐Ki Lee;I. Losito;J. Gardella;W. Hicks
本文报道了一种基于水解可降解聚酯和氟碳表面化学相结合的新型材料的合成和表征。这些材料的表面特性克服了聚合物材料在控制细胞或组织粘附特性方面的一些局限性。合成了两种长度的氟碳链(CF3（CF2)m（CH2)n，其中F7C1和F10C2分别代表m = 6和n = 1, m = 9和n = 2）作为l-和dl-聚乳酸（PLA）和聚乳酸-共糖醇）共聚物的末端基团。采用开环聚合和取代末端羟基上的碳氟化合物，得到了末端有1、2和4个碳氟化合物基团的聚酯（f -聚酯）。角依赖x射线光电子能谱（XPS或ESCA）显示，端基在表面是分离的。氟碳基团的表面覆盖率随浓度的增大而增大，且随浓度的增大而增大。
We report the synthesis and characterization of a new class of materials based on combining hydrolytically degradable polyesters and fluorocarbon surface chemistry. These materials have surface properties which overcome some of the limitations of polymeric materials in controlled cellular or tissue adhesion properties. Fluorocarbon chains of two lengths (CF3(CF2)m(CH2)n, where F7C1 and F10C2 represent m = 6 and n = 1 and m = 9 and n = 2, respectively) have been synthesized as the terminal end groups to l- and dl-polylactides (PLA) and poly(lactide-co-glycolide) copolymers. Using both ring-opening polymerization and the substitution of the fluorocarbon at terminal hydroxyl groups, polyesters with 1, 2, and 4 fluorocarbon end groups were obtained (F-polyesters). Angular dependent X-ray photoelectron spectroscopy (XPS or ESCA) revealed that end groups are segregated at the surface. Further, the results show their the surface coverage of fluorocarbon groups increases with increasing the concentration and the ...