Subject-specific models of the hindfoot reveal a relationship between morphology and passive mechanical properties
Subject-specific models of the hindfoot reveal a relationship between morphology and passive mechanical properties
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DOI：
10.1016/j.jbiomech.2007.12.017
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发表时间：
2008-01-01
影响因子：
2.4
通讯作者：
Toy, Jason R.
中科院分区：
文献类型：
--
作者：
Imhauser, Carl W.;Siegler, Sorin;Toy, Jason R.
据报道，骨骼、关节表面和韧带的形态以及踝关节复合体的被动力学特征在个体之间存在很大差异。这项研究的目的是验证一种假设，即在健康的踝关节复合体的被动机械特性中观察到的变化强烈地受到形态变化的影响。为了验证这一假说，我们根据6具身体小腿的MRI形态数据，以及关于韧带和关节软骨力学性能的平均报道数据，建立了6个踝关节复合体的数值模型。在不同的加载条件下，每个模型的被动力学行为被发现与从每个相应的试件获得的实验数据非常吻合。由于所有模型使用相同的材料特性，并受到相同的载荷和边界条件，因此得出结论，观察到的被动力学特性的变化是由于形态的变化，从而证实了这一假设。此外，模型之间观察到的被动力学行为的平均和较大差异与身体标本之间的实验观察结果相似。结果表明，针对踝关节复杂疾病的个体化治疗程序潜在地优于一刀切的方法。(C)2008爱思唯尔有限公司。保留所有权利。
The morphology of the bones, articular surfaces and ligaments and the passive mechanical characteristics of the ankle complex were reported to vary greatly among individuals. The goal of this study was to test the hypothesis that the variations observed in the passive mechanical properties of the healthy ankle complex are strongly influenced by morphological variations. To evaluate this hypothesis six numerical models of the ankle joint complex were developed from morphological data obtained from MRI of six cadaveric lower limbs, and from average reported data on the mechanical properties of ligaments and articular cartilage. The passive mechanical behavior of each model, under a variety of loading conditions, was found to closely match the experimental data obtained from each corresponding specimen. Since all models used identical material properties and were subjected to identical loads and boundary conditions, it was concluded that the observed variations in passive mechanical characteristics were due to variations in morphology, thus confirming the hypothesis. In addition, the average and large variations in passive mechanical behavior observed between the models were similar to those observed experimentally between cadaveric specimens. The results suggest that individualized subject-specific treatment procedures for ankle complex disorders are potentially superior to a one-size-fits-all approach. (c) 2008 Elsevier Ltd. All rights reserved.