Incidence and prognosis of early primary ventricular fibrillation in acute myocardial infarction - Results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2) database
Incidence and prognosis of early primary ventricular fibrillation in acute myocardial infarction - Results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2) database
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DOI：
10.1016/s0002-9149(98)00336-1
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发表时间：
1998-08-01
影响因子：
2.8
通讯作者：
Negri, E
中科院分区：
文献类型：
--
作者：
Volpi, A;Cavalli, A;Negri, E
Primary ventricular fibrillation (VF) complicating acute myocardial infarction (MI) predicts short-term mortality. The broad category of patients with primary VF might include subgroups with different outcomes. It is still not certain whether early-onset (less than or equal to 4 hours) primary VF is a risk predictor, and information on correlates of these early fibrillations is scarce. This study sought to prospectively analyze the incidence and prognosis of early, as opposed to late (time window >4 to 48 hours) primary VF and retrospectively identify predisposing factors for early-onset primary VF. We analyzed the incidence and recurrence rate of early and late primary VF in 9,720 patients with a first acute MI, treated with thrombolytics, enrolled in the Gruppo Italiano per to Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-2 trial, The independent prognostic significance of early and late primary VF was assessed by logistic regression analysis. The incidence rates of early and late primary VF were 3.1% and 0.6%, respectively; recurrence rates were 11% and 15%, respectively. The 2 variables most closely related to early primary VF were hypokalemia and systolic blood pressure
