Extremely facile and selective nickel-catalyzed allyl ether cleavage
Extremely facile and selective nickel-catalyzed allyl ether cleavage
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DOI：
10.1002/(sici)1521-3773(19980504)37:8
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发表时间：
1998-05-04
影响因子：
16.6
通讯作者：
Ogasawara, K
中科院分区：
文献类型：
--
作者：
Taniguchi, T;Ogasawara, K
小儿科！烯丙基醚作为羟基官能团的保护基团可以很容易地用DIBAL和催化量的[NiCl 2（dppp）]的组合除去。丙烯在该显著选择性的反应中被排出，并且提出了镍催化的氢化铝消除途径[Eq.（a）]。dppp=丙烷-1，3-二基双（二苯基膦）。
Child's play!Allyl ethers as protecting groups for hydroxyl functions can be removed readily with a combination of DIBAL and catalytic amounts of [NiCl2(dppp)]. Propene is expelled in this remarkably selective reaction, and a nickel‐catalyzed hydroalumination–elimination pathway is proposed [Eq. (a)]. dppp=propane‐1,3‐diylbis(diphenylphosphane).