ALTERATIONS IN CAT SKELETAL NEUROMUSCULAR-JUNCTIONS FOLLOWING PROLONGED INACTIVITY
ALTERATIONS IN CAT SKELETAL NEUROMUSCULAR-JUNCTIONS FOLLOWING PROLONGED INACTIVITY
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DOI：
10.1113/jphysiol.1981.sp013680
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发表时间：
1981-01-01
影响因子：
5.5
通讯作者：
STEINBACH, JH
中科院分区：
文献类型：
--
作者：
ELDRIDGE, L;LIEBHOLD, M;STEINBACH, JH
本文对失活2-3年的猫肌纤维乙酰胆碱（ACh）受体、胆碱酯酶（ChE）活性和神经末梢的分布进行了研究。神经肌肉接头的大小增加的结果发芽的终端分支。有些纤维在不同的部位有多重神经支配。在2只猫的肌肉，在交界处的一些地区表现出胆碱酯酶活性，但只有一个相对较低的ACh受体密度。连接外受体密度高于正常肌肉，但低于肌肉失神经长达10个月。
The distributions of acetylcholine (ACh) receptors, cholinesterase (ChE) activity and nerve terminals were studied on cat muscle fibers which had been inactive for 2-3 yr. Neuromuscular junctions increased in size as a result of sprouting of terminal branches. Some fibers were multiply innervated at separate sites. In muscles from 2 cats, some areas at the junction showed ChE activity but had only a relatively low density of ACh receptors. The extrajunctional receptor density was higher than in normal muscles but lower than in muscles denervated for up to 10 mo.