Abnormal gamma and beta MEG activity during finger movements in early-onset psychosis.
Abnormal gamma and beta MEG activity during finger movements in early-onset psychosis.
复制标题
早发性精神病患者手指运动期间异常的 γ 和 β MEG 活性。
DOI：
10.1080/87565641.2011.555573
复制
发表时间：
2011
影响因子：
1.5
通讯作者：
Rojas,DonaldC
中科院分区：
文献类型：
--
作者：
Wilson,TonyW;Slason,Erin;Asherin,Ryan;Kronberg,Eugene;Teale,PeterD;Reite,MartinL;Rojas,DonaldC
Patients with psychosis often exhibit abnormalities in basic motor control, but little is known about the neural basis of these deficits. This study examines the neuro-dynamics of movement using magnetoencephalography (MEG) in adolescents with early-onset psychosis and typically developing controls. MEG data were imaged using beamforming then evaluated for task and group effects before, during, and after movement onsets. Primary findings included weaker activation in patients during movement execution in cerebellar cortices. Such aberrations likely contribute to the decreased motor control exhibited by patients with psychosis, and may reflect GABAergic-based inhibitory deficits comparable to those seen in cellular and system-level studies.
