Office-based optical coherence tomographic imaging of human vocal cords

Office-based optical coherence tomographic imaging of human vocal cords
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DOI:
10.1117/1.2200371
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发表时间:
2006-05-01
影响因子:
3.5
通讯作者:
Wong, Brian J. F.
Wong, Brian J. F.
中科院分区:
医学3区
文献类型:
--
作者:
Guo, Shuguang;Hutchison, River;Wong, Brian J. F.

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光学相干断层成像(OCT)是一种发展中的非侵入性成像手段,已被用于外科内窥镜检查中的喉部成像。讨论了一种能够在典型的办公室喉镜检查中捕获人类喉部图像的OCT采样装置的设计。病人和医生的行动都得到了解决。展示了人体喉部的OCT活体成像。虽然长焦距限制了图像的横向分辨率,但仍然可以很容易地区分基底膜。基于办公室的OCT具有指导手术活检、指导治疗和监测疾病的潜力。这是一种很有前途的研究喉部的成像方法。(C)2006年光学仪器工程师学会。
Optical coherence tomography (OCT) is an evolving noninvasive imaging modality and has been used to image the larynx during surgical endoscopy. The design of an OCT sampling device capable of capturing images of the human larynx during a typical office based laryngoscopy examination is discussed. Both patient's and physician's movements were addressed. In vivo OCT imaging of the human larynx is demonstrated. Though the long focal length limits the lateral resolution of the image, the basement membrane can still be readily distinguished. Office-based OCT has the potential to guide surgical biopsies, direct therapy, and monitor disease. This is a promising imaging modality to study the larynx. (c) 2006 Society of Photo-Optical Instrumentation Engineers.