The magnetocardiogram as derived from electrocardiographic data.
The magnetocardiogram as derived from electrocardiographic data.
复制标题
从心电图数据导出的心磁图。
DOI：
10.1161/01.res.67.6.1503
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发表时间：
1990
影响因子：
20.1
通讯作者：
H. T. ter Brake
中科院分区：
文献类型：
--
作者：
A. van Oosterom;T. Oostendorp;G. Huiskamp;H. T. ter Brake
心脏磁图信号存在于胸腔外，由人类心脏心室内的去极化过程产生，已经通过使用将均匀双层作为唯一主要来源的模型进行了计算。体积导体效应是通过使用胸腔的非均匀、多室模型来处理的，该模型基于源自磁共振成像的“量身定制”几何形状。所需的激活函数，指定心室去极化过程的时间，是从使用在体表测量的电信号作为输入数据的反向程序中导出的。接下来，测量来自同一受试者的磁信号。计算得到的磁信号与测量得到的磁信号非常接近（相对均方根残差为0.37）。这些结果表明，心磁图和心电图具有共同的基础，并且不太可能存在与心脏去极化过程相关的磁场成因中存在电沉默但活跃的突出来源。此外，还为经典的均匀双层电模型在心室去极化过程中的有效性提供了新的支持。以前已经发现二次源的贡献是电信号的主要组成部分；它们现在也被证明是磁信号的主要组成部分。
Magnetocardiographic signals, as present outside the thorax and generated by the depolarization process within the ventricles of the human heart, have been computed by using a model that incorporates the uniform double layer as the exclusive primary source. The volume conductor effects are treated by using an inhomogeneous, multicompartmental model of the thorax, based on "tailored" geometry derived from magnetic resonance imaging. The required activation function, specifying the timing of the ventricular depolarization process, was derived from an inverse procedure that uses as input data electric signals measured at the body surface. Next, the magnetic signals from the same subjects were measured. A close correspondence between computed and measured magnetic signals was observed (relative root mean square residual difference of 0.37). These results demonstrate that magnetocardiograms and electrocardiograms have a common basis and that it is unlikely that prominent sources exist that are electrically silent and yet active in the genesis of the magnetic fields associated with the depolarization process of the heart. Moreover, fresh support is implied for the usefulness of the classical uniform double layer as the electrical source model during ventricular depolarization. The contributions of the secondary sources have previously been found to be a major component of the electric signals; they are now also shown to be a major component of the magnetic signals.
影响因子：
3.4
作者：
Roth,BJ;WikswoJr,JP
通讯作者：
WikswoJr,JP