An epidermal factor which induces thyroid hormone-dependent regression of mesenchymal tissues of the tadpole tail.
An epidermal factor which induces thyroid hormone-dependent regression of mesenchymal tissues of the tadpole tail.
复制标题
诱导蝌蚪尾间质组织甲状腺激素依赖性退化的表皮因子。
DOI：
10.1016/0012-1606(86)90097-7
复制
发表时间：
1986
影响因子：
2.7
通讯作者：
K. Yoshizato
中科院分区：
文献类型：
--
作者：
K. Niki;K. Yoshizato
蝌蚪尾部皮肤的外植体分泌一种诱导甲状腺激素依赖性尾部间质退化的因子。该因子的活性对胰蛋白酶或链霉蛋白酶的消化不敏感。在 120°C 但不在 100°C 加热 20 分钟破坏了活性。该因子通过透析膜逐渐排出。该因子在 Sephadex G-10 柱上延迟，并在盐级分后用水洗脱。我们认为活性成分是低分子量的非蛋白质物质。
Explants of tadpole tail skin secreted a factor which induces the thyroid hormone-dependent regression of the tail mesenchyme. The activity of the factor was not sensitive to digestion with trypsin or pronase. Heating at 120°C but not at 100°C for 20 min destroyed the activity. The factor came out gradually through a dialysis membrane. The factor was retarded on a Sephadex G-10 column and eluted with water after the salts fraction. We suggest that the active principle is a non-proteinaceous substance with a low molecular weight.