Evans' syndrome associated with Graves' disease
Evans' syndrome associated with Graves' disease
复制标题
DOI：
10.2169/internalmedicine.35.987
复制
发表时间：
1996-12-01
影响因子：
1.2
通讯作者：
Saito, N
中科院分区：
文献类型：
--
作者：
Yashiro, M;Nagoshi, H;Saito, N
一名患有格雷夫斯病6年的36岁女性因严重的血小板减少症入院治疗。诊断为Evans‘s综合征，患者家族史显示多例Graves’病，但无Evans‘s综合征病例，两种情况经皮质类固醇和甲氨咪唑治疗后均有所改善，发现多种自身免疫抗体，但共同的自身免疫机制尚未明确显示，虽然Graves病和Evans’s综合征的合并在她的家族中没有发生过，但遗传因素可能在这两种疾病的发病机制中起着重要作用。
A 36-year-old woman who had had Graves' disease for 6 years was admitted with severe thrombocytopenia. Evans' syndrome was diagnosed, The patient's family history showed multiple cases of Graves' disease but no cases of Evans' syndrome, Both conditions in this patient improved with corticosteroid and thiamazole therapy, Several autoimmune antibodies were found, but a common autoimmune mechanism was not clearly shown, Although the combination of Graves' disease and Evans' syndrome had not occurred previously in her family, genetic factors may play an important role in the pathogenesis of both conditions.