Facilitation of probabilistic classification learning by transcranial direct current stimulation of the prefrontal cortex in the human
Facilitation of probabilistic classification learning by transcranial direct current stimulation of the prefrontal cortex in the human
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DOI：
10.1016/s0028-3932(03)00124-6
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发表时间：
2004-01-01
期刊：
影响因子：
2.6
通讯作者：
Paulus, W
中科院分区：
文献类型：
--
作者：
Kincses, TZ;Antal, A;Paulus, W
本研究的目的是测试是否前额叶皮层（PFC）的电刺激可以修改概率分类学习（PCL）。经颅直流电刺激（tDCS）管理的左前额叶和初级视觉皮层的22名健康受试者，而他们进行了PCL任务。在这项任务中，受试者学习在呈现特定的线索组合后，每次试验会出现两种结果中的哪一种。十分钟的阳极刺激，而不是阴极刺激，改善内隐学习只有当左PFC被刺激。我们的研究结果表明，隐式PLC可以修改弱的阳极tDCS，这可能会增加神经兴奋性，如先前在运动和视觉皮层中所示。我们的结果表明，有必要进一步研究tDCS对学习和记忆过程的促进作用。(C)2003 Elsevier Ltd.保留所有权利。
The aim of our study was to test if the electrical stimulation of the prefrontal cortex (PFC) could modify probabilistic classification learning (PCL). Transcranial direct current stimulation (tDCS) was administered to the left prefrontal and to the primary visual cortex of 22 healthy subjects while they performed a PCL task. In this task subjects learned which of two outcomes would occur on each trial after presentation of a particular combination of cues. Ten minutes of anodal, but not cathodal, stimulation improved implicit learning only when the left PFC was stimulated. Our results show that implicit PLC can be modified by weak anodal tDCS, which probably increases neural excitability, as has been shown in the motor and visual cortices previously. Our results suggest that further studies on the facilitation of learning and memory processes by tDCS are warranted. (C) 2003 Elsevier Ltd. All rights reserved.