HBV mutations in EnhII/BCP/PC region contribute to the prognosis of hepatocellular carcinoma

HBV mutations in EnhII/BCP/PC region contribute to the prognosis of hepatocellular carcinoma
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HBV EnhII/BCP/PC区突变有助于肝细胞癌的预后

DOI:
10.1002/cam4.2169
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发表时间:
2019-06-01
期刊:
影响因子:
4
通讯作者:
Hu, Zhibin
Hu, Zhibin
中科院分区:
医学3区
文献类型:
--
作者:
Ge, Zijun;Tian, Ting;Hu, Zhibin

文献摘要

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Accompanied by HBV infection, HBV mutations gradually occur because HBV polymerase appears proofread deficiencies. In our previous study, we have identified that EnhII/BCP/PC mutations and genotype C of HBV DNA were associated with hepatocellular carcinoma (HCC) risk. In this study, we extend our research to explore HCC prognosis associated genotype and mutations in EnhII/BCP/PC regions.