Incidence rates of salivary gland tumors: Results from a population-based study
Incidence rates of salivary gland tumors: Results from a population-based study
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DOI：
10.1016/s0194-5998(99)70323-2
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发表时间：
1999-06-01
影响因子：
3.4
通讯作者：
Cole, P
中科院分区：
文献类型：
--
作者：
Pinkston, JA;Cole, P
涎腺肿瘤是不常见的，其流行病学尚未得到很好的描述。我们对亚拉巴马州杰斐逊县医院1968年至1989年新诊断的腮腺、颌下和舌下腺肿瘤进行了描述性流行病学研究。发病率是根据1979年至1980年、1983年至1984年或1987年至1988年诊断的病例的一个以人群为基础的子集估计的。良性占84.3%，恶性占15.7%。腮腺占86%，颌下腺占14%。未发现舌下腺肿瘤。良性混合瘤最多见（65.6%），其次为沃辛瘤（29.2%），恶性粘液表皮样癌最多见（51.3%）。良性肿瘤年平均发病率为4.7/10万，恶性肿瘤年平均发病率为0.9/10万。良性和恶性肿瘤的发病率随着年龄的增长而增加，直到65至74岁，然后下降。良性混合瘤多见于女性，Warthin瘤和恶性肿瘤多见于男性（P < 0.05），Warthin瘤在黑人中少见（P < 0.001）。我们的结论是，唾液腺肿瘤是一种罕见的，但流行病学多样化的肿瘤组。其原因也可能各不相同。
Salivary gland tumors are uncommon, and their epidemiology has not been well described. We conducted a descriptive epidemiologic study of parotid, submaxillary, and sublingual gland tumors newly diagnosed in Jefferson County, Alabama, hospitals from 1968 to 1989, Incidence rates were estimated with a population-based subset of cases diagnosed during the years 1979 to 1980, 1983 to 1984, or 1987 to 1988, Among 248 incident cases, 84.3% were benign and 15.7% were malignant, Eighty-six percent of cases arose in the parotid gland, and 14% arose in the submaxillary gland. No sublingual gland tumor was identified. The benign mixed tumor was the most frequent tumor (65.6%), followed by Warthin's tumor (29.2%), Mucoepidermoid carcinoma was the most frequent malignant tumor (51.3%), The average annual age-adjusted incidence rate per 100,000 was 4.7 for benign tumors and 0.9 for malignant tumors. Incidence rates for both benign and malignant tumors increased with age until ages 65 to 74 years and then declined. Benign mixed tumors occurred more frequently in female patients, whereas Warthin's tumors and malignant tumors occurred more frequently in male patients (P < 0.05), Warthin's tumor was rare in black patients (P < 0.001). We conclude that salivary gland tumors are an uncommon but epidemiologically diverse group of tumors. Their causes are also likely to differ.