Microcytic anemia secondary to intraperitoneal aluminum in normal and uremic rats.
Microcytic anemia secondary to intraperitoneal aluminum in normal and uremic rats.
复制标题
正常和尿毒症大鼠腹腔内铝继发的小细胞性贫血。
DOI：
10.1038/ki.1984.169
复制
发表时间：
1984
影响因子：
19.6
通讯作者：
Mayor,GH
中科院分区：
文献类型：
--
作者：
Kaiser,L;Schwartz,KA;Burnatowska-Hledin,MA;Mayor,GH
方法4组雄性Sprague-Dawley大鼠（225 ~ 240 g）自由饮用去离子蒸馏水和标准饲料（韦恩实验室Blox，芝加哥，伊利诺伊州）。在5天适应后，用甲氧氟烷轻度麻醉动物，并从眶后窦获得约200 rl血液用于全血（CBC）和网织红细胞计数（C1=术前对照期）。第二天，将动物随机分配至尿毒症组或假手术组，并用腹膜内戊巴比妥（50 mg/kg）麻醉。
Methods Four groups of male Sprague-Dawley rats (225 to 240 g) were allowed free access to deionized distilled water and standard diet (Wayne Lab Blox, Chicago, Illinois). After a 5-day acclimation, animals were lightly anesthetized with methoxyflurane and approximately 200 rl blood obtained from the retroorbital sinus for complete blood (CBC) and reticulocyte counts (C1= preoperative control period). The following day animals were randomly assigned to either uremic or sham-operated groups and anesthetized with intraperitoneal pentobarbital (50 mg/kg).