Changes in body composition of cancer patients following combined nutritional support.
Changes in body composition of cancer patients following combined nutritional support.
复制标题
DOI：
10.1080/01635588209513746
复制
发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
Ellis, K J
中科院分区：
文献类型：
--
作者：
Cohn, S H;Vartsky, D;Ellis, K J
对无法维持正常营养的癌症患者进行了联合营养支持(肠外、肠内和口服)的效果评估。身体成分的变化通过测量全身氮、钾、水和脂肪的水平来量化。采用膳食调查法(4天回忆法)评价患者的蛋白质热量摄入量。用于营养评估的标准人体测量和生化测量用于比较。膳食评估表明，所有患者的膳食补充足以满足他们的能量需求。在联合营养支持方案中，几乎所有患者的体重都增加了。对身体成分的测定表明，体重的变化等于身体蛋白质、总水分和总脂肪变化的总和。人体测量营养指数(上臂肌围和三头肌皮褶)的结果与身体成分研究的结果一致。通过将身体成分数据与正常组织的蛋白质：水：瘦体重的比率进行比较，获得关于组织性质的信息。癌症患者的蛋白质平均增加很少(0.3-0.6公斤)。体重的主要变化似乎是体内水分和脂肪增加的结果。体内总氮与钾的比率用来定义高营养后组织合成代谢的程度。在癌症患者中，在高营养后，这一比例下降了，接近于服用双脂饮食的对照组的值。所描述的身体隔室技术已经证明了它们在确定高营养对癌症患者的影响方面的有效性。
The effects of combined nutritional support (parenteral, enteral, and oral) were measured in cancer patients unable to maintain normal alimentation. Changes in body composition were quantified by measurement of total body levels of nitrogen, potassium, water, and fat. The protein-calorie intake of the patients was also evaluated by dietary survey (4-day recall). Standard anthropometric and biochemical measurements for nutritional assessment were obtained for comparison. The dietary evaluation indicated that the dietary supplementation for all patients was more than adequate to meet their energy requirements. Almost all patients gained weight on the combined nutritional support regimens. Determination of body composition indicated that change in body weight was equal to the sum of the changes in body protein, total body water, and total body fat. The findings from the anthropometric nutrition indices (arm muscle circumference and triceps skinfold) were consistent with the results of the body composition study. Information on the nature of the tissue gained was obtained by comparison of body composition data with the ratio of protein:water:lean body mass for normal tissue. The mean gain of protein in the cancer patients was quite small (0.3-0.6 kg). The main change in body weight appeared to be the result of gains in body water and body fat. The total body nitrogen to potassium ratio served to define the extent of tissue anabolism following hyperalimentation. The ratio dropped in the cancer patients following hyperalimentation toward the value of the control subjects on ad libidum diets. The body compartment techniques described have demonstrated their usefulness in determining the effects of hyperalimentation on cancer patients.