Effect of X-ray Irradiation on Articular Cartilage Mechanical Properties
Effect of X-ray Irradiation on Articular Cartilage Mechanical Properties
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DOI：
10.12693/aphyspola.129.200
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发表时间：
2016-02-01
影响因子：
0.7
通讯作者：
Cicek, E.
中科院分区：
文献类型：
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作者：
Cicek, E.
关节软骨是一种在关节骨骼末端发现的承载组织，为有效运动提供低摩擦表面。它的力学性能是由II型胶原蛋白、蛋白聚糖和间质液的结构和组成决定的。本研究利用偏振光显微镜成像和关节软骨压缩模量测试来确定电离辐射对关节软骨力学性能的影响，研究了x射线辐照对关节组织生物特性的影响。测试结果显示，对照组的松弛时间明显比x射线暴露的样品长，而力则大得多，说明x射线照射导致关节软骨刚度降低。
A load bearing tissue found at the ends of articulating bones, the articular cartilage provides low friction surfaces for efficient movement. Its mechanical properties are determined by the structure and composition of type II collagen, proteoglycans and interstitial fluid. This work investigates the effects of X-ray irradiation, previously shown to affect the biological properties of the articular tissue, on mechanical properties of articular cartilage using polarized light microscope for imaging and compressive modulus test applied to articular cartilage to determine the effects of the ionizing radiation on mechanical properties. According to the test results, the relaxation time is significantly longer in control than X-ray exposed samples, while the force is much higher showing that the X-ray irradiation causes the reduction in the stiffness of articular cartilage.