The risk of missing angle neovascularization by omitting screening gonioscopy in acute central retinal vein occlusion
The risk of missing angle neovascularization by omitting screening gonioscopy in acute central retinal vein occlusion
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DOI：
10.1016/s0161-6420(98)95014-x
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发表时间：
1998-05-01
期刊：
影响因子：
13.7
通讯作者：
Zhang, ZY
中科院分区：
文献类型：
--
作者：
Browning, DJ;Scott, AQ;Zhang, ZY
目的：本研究的目的是确定视网膜中央静脉阻塞（CRVO）中无瞳孔边缘新生血管的情况下是否可以发生房角新生血管。设计：该研究设计是对主要问题的前瞻性研究和对辅助问题的回顾性研究。参与者：作者检查了 1986 年 7 月 1 日至 3 月 18 日期间有缺血临床证据的 100 名 CRVO 患者的 105 只眼睛， 1996.干预：作者使用未散瞳裂隙灯生物显微镜和蔡司四镜前房角镜检查来寻找虹膜和房角新生血管。主要结果测量：测量前段新生血管的存在。结果：在 34 只发生前段新生血管的眼睛中，4 只（12%）在平均随访 2.2 +/- 的时间内出现房角新生血管，但没有瞳孔边缘新生血管。 2.4标准差年。结论：CRVO中无瞳孔边缘受累的情况下也可发生房角新生血管，这意味着有必要进行前房角镜检查并支持中央静脉阻塞研究的结论（基于临床上未使用的摄影技术）。
Objective: The purpose of the study was to determine whether angle neovascularization can occur without pupillary margin neovascularization in central retinal vein occlusion (CRVO).Design: The study design was a prospective study of the main question and a retrospective study of ancillary issues.Participants: The authors examined 105 eyes of 100 patients with CRVO having clinical evidence of ischemia between July 1, 1986, and March 18, 1996.Intervention: The authors looked for iris and angle neovascularization with both undilated slit-lamp biomicroscopy and Zeiss four-mirror gonioscopy.Main Outcome Measures: The presence of anterior segment neovascularization was measured.Results: Of 34 eyes developing anterior segment neovascularization, 4 (12%) developed angle neovascularization without pupillary margin neovascularization over a mean follow-up of 2.2 +/- 2.4 standard deviation years.Conclusions: Angle neovascularization can occur without pupillary margin involvement in CRVO, implying the necessity of screening gonioscopy and supporting the Central Vein Occlusion Study conclusion (based on a photographic technique not used clinically).