Electron beam irradiation of typical sulfonamide antibiotics in the aquatic environment: Kinetics, removal mechanisms, degradation products and toxicity assessment.
Electron beam irradiation of typical sulfonamide antibiotics in the aquatic environment: Kinetics, removal mechanisms, degradation products and toxicity assessment.
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DOI：
10.1016/j.chemosphere.2021.129713
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发表时间：
2021-01
期刊：
影响因子：
8.8
通讯作者：
Feng Zhu;Jiali Pan;Qi Zou;Minghong Wu;Hongyong Wang;Gang Xu
中科院分区：
文献类型：
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作者：
Feng Zhu;Jiali Pan;Qi Zou;Minghong Wu;Hongyong Wang;Gang Xu
由于磺胺类抗生素的广泛使用和对水环境的危害，磺胺类抗生素已成为一种备受关注的新兴污染物。本论文研究了磺胺甲基嘧啶（SMR）、磺胺嘧啶（SDZ）和磺胺吡啶（SPD）在电子束辐照下的降解过程和机理。结果表明，3种水杨酸均符合准一级反应动力学，在5 kGy剂量下，几乎可以完全去除。在环境因素中，pH（3.0）和O2气氛能进一步促进磺胺类药物的去除，而NO2-对磺胺类药物的降解抑制作用最明显，说明羟基自由基起主导作用.与SMR和SDZ相比，低分子量SPD的矿化程度明显（45%）。LC-MS和DFT计算结果表明，3种SA的降解产物浓度均呈现先升高后降低的趋势，表明EBI能够实现SA的高效去除和进一步矿化。同时，对降解过程中产生的共同产物4-氨基苯酚的研究结果进一步表明，HO自由基点是主要的活性氧物种（ROS）。此外，发光细菌急性毒性实验和ECOSAR程序预测表明，降解后的毒性效应大大降低。该研究为实现水环境中新兴污染物的高效和深度去除提供了新的思路。
Due to their widespread use and harmful effects on aquatic environment, sulfonamide antibiotics (SAs) have become an emerging pollutant of great concern around the world. In this study, we investigated the degradation process and mechanism of sulfamerazine (SMR), sulfadiazine (SDZ), and sulfapyridine (SPD) by electron-beam irradiation (EBI). The results showed that the three SAs were well suited to the pseudo-first-order reaction kinetics, and they could be almost completely removed with high efficiency (5 kGy). Among the environmental factors, pH (3.0) and O2atmosphere can further enhance the removal of the sulfonamides (SAs), while NO2−has the most pronounced degrading inhibitory effects among the many ions, these results illustrate that hydroxyl radicals play a dominant role. Compared with SMR and SDZ, the degree of mineralization of lower molecular weight SPD is obvious (45%). LC-MS and DFT calculations indicate that the concentrations of degradation products of the three SAs show a tendency to increase and then decrease, demonstrating that EBI can achieve efficient removal and further mineralization of SAs. Meanwhile, the results of the common product 4-Aminophenol produced during the degradation process further indicate that HOradical dot is the predominant reactive oxygen species (ROS). In addition, acute toxicity experiments with luminescent bacteria and predictions of ECOSAR procedures proved the toxic effects greatly decreased after the degradation. This study provides new ideas for achieving efficient and profound removal of emerging pollutants from the aquatic environment.