Cycloaddition of arynes with iodonium ylides: a mild and general route for the synthesis of benzofuran derivatives
Cycloaddition of arynes with iodonium ylides: a mild and general route for the synthesis of benzofuran derivatives
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芳炔与碘叶立德的环加成：合成苯并呋喃衍生物的温和通用路线
DOI：
10.1021/ol800051k
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发表时间：
2008-04-17
期刊：
影响因子：
5.2
通讯作者：
Li, Jin-Heng
中科院分区：
文献类型：
--
作者：
Huang, Xiao-Cheng;Liu, Yi Lin;Li, Jin-Heng
本文报道了芳炔与碘鎓叶立德的温和而普遍的环加成反应。在CsF存在下，邻位甲硅烷基芳基三氟甲磺酸酯与碘鎓叶立德在室温下以中等至良好的产率顺利反应。
A mild and general cycloaddition of arynes with iodonium ylides protocol has been developed for the synthesis of benzofurans. In the presence of CsF, ortho-silyl aryltriflates were reacted with iodonium ylides smoothly at room temperature in moderate to good yields.