Comparison of OCT Measurements between High Myopic and Low Myopic Children
Comparison of OCT Measurements between High Myopic and Low Myopic Children
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DOI：
10.1097/opx.0000000000000086
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发表时间：
2013-12-01
影响因子：
1.4
通讯作者：
Chun, Bo Young
中科院分区：
文献类型：
--
作者：
Lim, Hyun-Taek;Chun, Bo Young
目的。方法比较10岁以下儿童高度近视眼和低度近视眼的视网膜神经纤维层厚度、黄斑厚度和黄斑总体积。前瞻性、随机、对照研究。对15例高度近视儿童(屈光度大于或等于-6.0 D，第1组)和20例低度近视儿童(屈光度0<-0.25~-3.0D，第2组)进行了时间域光学相干断层扫描(Stratus OCT；Carl Zeiss Meditec)。两组均行快速RNFL扫描和快速黄斑OCT扫描。作者对两组的数据进行了比较。高度近视组平均年龄为7.8岁，低度近视组平均年龄为7.2岁。高度近视组视网膜神经纤维层平均厚度为100.8微米，低度近视组为110.5微米。两组间RNFL厚度差异有统计学意义(p<；0.05)。此外，高度近视儿童下象限视盘周围视网膜层变薄尤为明显(p=0.021)。高度近视组黄斑厚度和体积的平均值也显著小于低度近视组(p<；0.05)。高度近视儿童的下象限和整个视乳头周围RNFL较低度近视儿童明显变薄。高度近视儿童黄斑厚度明显变薄，黄斑体积变小。在高度近视儿童的临床评估中应考虑这些结构性差异。
Purpose. To compare the peripapillary retinal nerve fiber layer (RNFL) thickness, macular thickness, and total macular volume of high myopic eyes with those of low myopic eyes in children younger than 10 years.Methods. Prospective, randomized, comparative study. Time-domain optical coherence tomography (OCT) (Stratus OCT; Carl Zeiss Meditec) was performed on 15 children with high myopia (refractive error greater than or equal to -6.0 diopters [D], group 1) and 20 children with low myopia (0 less than refractive error from -0.25 to -3.0 D, group 2). Fast RNFL scan and a fast macular scan with OCT were performed in both groups. The authors compared the data between the two groups.Results. The mean age of the patients with high myopia was 7.8 years and that of those with low myopia was 7.2 years. The mean overall thickness of the peripapillary RNFL was 100.8 mu m in the high myopes and 110.5 mu m in the low myopes. There was a statistically significant difference in the overall RNFL thickness between the two groups (p < 0.05). In addition, peripapillary RNFL thinning was especially prominent in the inferior quadrant in children with high myopia (p = 0.021). The mean values of macula thickness and volume for high myopes were also significantly smaller than the mean values for low myopes (p < 0.05).Conclusions. The inferior quadrant and the overall peripapillary RNFL were significantly thinner in high myopic children relative to low myopic children. High myopic children had significantly thinner macular thickness and lower macular volumes. These structural differences should be considered in the clinical assessment of high myopic children.