Histoplasmosis among hospitalized febrile patients in northern Tanzania
Histoplasmosis among hospitalized febrile patients in northern Tanzania
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DOI：
10.1016/j.trstmh.2012.05.009
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发表时间：
2012-08-01
影响因子：
2.2
通讯作者：
Crump, John A.
中科院分区：
文献类型：
--
作者：
Lofgren, Sarah M.;Kirsch, Emily J.;Crump, John A.
组织胞浆菌病在东非可能很常见，但诊断很少得到证实。我们报告在坦桑尼亚北部970例发热住院患者中回顾性发现的9例（0.9%）可能的组织胞浆菌病。年龄中位数（范围）为31岁（6,44）岁，女性6例（67%），艾滋病毒感染者6例（67%）；7例（78%）临床诊断为结核或细菌性肺炎。组织胞浆菌病是坦桑尼亚发热性疾病的重要病因，但在鉴别诊断中很少被考虑。提高临床医生的认识和可靠诊断测试的可用性可能会改善患者的预后。(C) 2012年皇家热带医学与卫生学会。Elsevier Ltd.出版。版权所有。
Histoplasmosis may be common in East Africa but the diagnosis is rarely confirmed. We report 9 (0.9%) cases of probable histoplasmosis retrospectively identified among 970 febrile inpatients studied in northern Tanzania. Median (range) age was 31(6, 44) years, 6 (67%) were female, 6 (67%) HIV-infected; 7 (78%) were clinically diagnosed with tuberculosis or bacterial pneumonia. Histoplasmosis is an important cause of febrile illness in Tanzania but is rarely considered in the differential diagnosis. Increased clinician awareness and availability of reliable diagnostic tests may improve patient outcomes. (C) 2012 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.