High-Resolution Diffusion Tensor Imaging With Inner Field-of-View EPI

High-Resolution Diffusion Tensor Imaging With Inner Field-of-View EPI
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DOI:
10.1002/jmri.21717
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发表时间:
2009-04-01
影响因子:
4.4
通讯作者:
Finsterbusch, Juergen
Finsterbusch, Juergen
中科院分区:
医学2区
文献类型:
--
作者:
Finsterbusch, Juergen

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目的:证明基于空间二维选择性射频激励的内视场(FOV)回波平面成像对高分辨率扩散张量成像的适用性。材料和方法。在 3 T 全身 MR 系统上对人脑和颈脊髓进行面内分辨率为 0.90 x 0.90 mm(2) 和 0.50 x 0.50 mm(2) 的内部 FOV 扩散张量成像。结果:使用内部 FOV 减少了平面回波成像中的几何畸变,并提高了面内分辨率。脑干中桥脑横纤维与锥体束的一些交叉点可以被解析,小脑白质中可以识别出增加的扩散各向异性和纤维取向,并且可以检测到脊髓灰质的扩散各向异性降低。结论:内视场回波平面成像可能有助于提高空间分辨率,从而提高人类中枢神经系统中扩散各向异性和白质纤维取向测量的准确性。
Purpose: To demonstrate the applicability of inner field-of-view view (FOV) echo-planar imaging based on spatially two-dimensional selective radiofrequency excitations to high-resolution diffusion tensor imaging.Materials and Methods. Diffusion tensor imaging of inner FOVs with In-plane resolutions of 0.90 x 0.90 mm(2) and 0.50 x 0.50 mm(2) was performed in the human brain and cervical spinal cord on a 3 T whole-body MR system.Results: Using inner FOVs reduces geometric distortions in echo-planar imaging and allows for an improved in-plane resolution. Some of the crossings of transverse pontine fibers with the pyramidal tracts In the brainstem could be resolved, increased diffusion anisotropy and fiber orientation could be identified In cerebellar white matter, and the reduced diffusion anisotropy of spinal cord gray matter could be detected.Conclusion: Inner FOV echo-planar Imaging may help to Improve the spatial resolution and thus the accuracy of diffusion anisotropy and white matter fiber orientation measurements in the human central nervous system.