Conformationally imprinted receptors: atropisomers with "write", "save", and "erase" recognition properties.
Conformationally imprinted receptors: atropisomers with "write", "save", and "erase" recognition properties.
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DOI：
10.1021/ol051325t
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发表时间：
2005-08
期刊：
影响因子：
5.2
通讯作者：
Charles F Degenhardt;J. Lavin;Mark D. Smith;K. Shimizu
中科院分区：
文献类型：
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作者：
Charles F Degenhardt;J. Lavin;Mark D. Smith;K. Shimizu
[反应：见正文] 提出了一种具有“写入”、“保存”和“擦除”识别特性的阻转异构受体。当在 9-腺嘌呤-9-醋酸乙酯客体分子存在下加热时，受体会采用互补构象。这种互补的氢键构象在冷却至室温时由于受限旋转的重新建立而被“保存”，并且即使在去除客体后也是稳定的。最后，在客体不存在的情况下，通过加热可以“擦除”阻转异构受体。
[reaction: see text] An atropisomeric receptor with "write", "save", and "erase" recognition properties is presented. The receptor adopts a complementary conformation when heating in the presence of an ethyl adenine-9-acetate guest molecule. This complementary hydrogen bonding conformation is "saved" upon cooling to room temperature due to the reestablishment of restricted rotation and is stable even upon removal of the guest. Finally, the atropisomeric receptor can be "erased" by heating in the absence of the guest.