Experimental determination of the permeability in the lacunar-canalicular porosity of bone.
Experimental determination of the permeability in the lacunar-canalicular porosity of bone.
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DOI：
10.1115/1.3200908
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发表时间：
2009-10
期刊：
影响因子：
--
通讯作者：
Cardoso L
中科院分区：
文献类型：
--
作者：
Gailani G;Benalla M;Mahamud R;Cowin SC;Cardoso L
Permeability of the mineralized bone tissue is a critical element in understanding fluid flow occurring in the lacunar-canalicular porosity (PLC) compartment of bone and its role in bone nutrition and mechanotransduction. However, the estimation of bone permeability at the tissue level is affected by the influence of the vascular porosity (PV) in macroscopic samples containing several osteons. In this communication, both analytical and experimental approaches are proposed to estimate the lacunar-canalicular permeability in a single osteon. Data from an experimental stress-relaxation test in a single osteon is used to derive the PLC permeability by curve fitting to theoretical results from a compressible transverse isotropic poroelastic model of a porous annular disk under a ramp loading history. The PLC tissue intrinsic permeability in the radial direction of the osteon was found to be dependent on the strain rate used and within the range of O(10−24)−O(10−25). The reported values of PLC permeability are in reasonable agreement with previously reported values derived using FEA and nanoindentation approaches.
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影响因子：
--
作者：
ASCENZI, A;BONUCCI, E
通讯作者：
BONUCCI, E
影响因子：
2.4
作者：
Wu, JZ;Herzog, W
通讯作者：
Herzog, W
DOI：
10.1115/1.2834881
发表时间：
1998-12-01
影响因子：
1.7
作者：
Zhang, D;Weinbaum, S;Cowin, SC
通讯作者：
Cowin, SC
影响因子：
--
作者：
Cooper, D. M. L.;Turinsky, A. L.;Hallgrimsson, B.
通讯作者：
Hallgrimsson, B.
DOI：
10.1115/1.3138475
发表时间：
1984-01-01
影响因子：
1.7
作者：
ARMSTRONG, CG;LAI, WM;MOW, VC
通讯作者：
MOW, VC