Primary lymphoma of CNS, mycophenolate mofetil and lupus

Primary lymphoma of CNS, mycophenolate mofetil and lupus
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DOI:
10.1177/0961203306071431
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发表时间:
2006-01-01
期刊:
影响因子:
2.6
通讯作者:
Prasad, A.
Prasad, A.
中科院分区:
医学4区
文献类型:
--
作者:
Finelli, P. F.;Naik, K.;Prasad, A.

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已知恶性增殖性疾病使免疫抑制治疗复杂化,并且先前已经描述了与霉酚酸酯(MMF)治疗相关的两例CNS原发性淋巴瘤(PCNSL)。我们报告第三例PCNSL的狼疮性肾病患者,而对霉酚酸酯治疗。考虑到在免疫抑制剂反应性疾病中MMF的使用增加,PCNSL可能更常见。
Lymphoproliferative disorders are known to complicate immunosuppressive therapy and two cases of primary lymphoma of CNS (PCNSL) have previously been described in association with mycophenolate mofetil (MMF) treatment. We report the third case of PCNSL in a patient with lupus nephropathy while on MMF treatment. PCNSL may be seen more frequently considering the increased use of MMF in immunosuppressant responsive conditions.