Association of geriatric conditions and cardiovascular diseases with disability in older adults with diabetes: Findings from a nationally representative survey
Association of geriatric conditions and cardiovascular diseases with disability in older adults with diabetes: Findings from a nationally representative survey
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DOI：
10.1111/j.1447-0594.2012.00935.x
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发表时间：
2013-07-01
影响因子：
3.3
通讯作者：
Wang, Hui-Hsuan
中科院分区：
文献类型：
--
作者：
Li, Chia-Lin;Chiu, Yi-Chen;Wang, Hui-Hsuan
目的：研究糖尿病与心血管疾病（高血压、心脏病和中风）和老年疾病（认知障碍和抑郁症状）的结合如何影响老年人残疾的几率。研究方法：我们分析了2005年台湾国民健康访问调查中65岁及以上人群（n=2727）的全国代表性样本数据。共有473名参与者有自我报告的医生诊断的糖尿病史。残疾定义为报告日常生活活动（ADL）、工具性日常生活活动（IADL）或一般体力活动（GPA）中一项或多项任务的限制。简易精神状态检查用于评估认知功能。流行病学研究中心抑郁量表用于评估抑郁症状。结果如下：在调整其他因素后，心血管疾病和老年疾病独立地导致糖尿病参与者的残疾几率过高。患有糖尿病合并心血管疾病和老年疾病的参与者的ADL，IADL和GPA残疾的比值比分别为18.02（95%CI 5.13-63.34），7.95（95%CI 4.07-15.50）和5.89（95%CI 3.19-10.90）。结论：我们的研究结果强调了糖尿病患者中心血管疾病与老年疾病并存的高患病率。此外，这些疾病和病症的综合存在与残疾的额外几率密切相关。这些发现强调了预防心血管疾病发病率，改善抑郁情绪和认知功能以降低老年糖尿病患者残疾风险的至关重要性。Geriatr Gerontol Int 2013; 13：563-570.
Aim: To examine how diabetes in combination with cardiovascular diseases (hypertension, heart disease and stroke) and geriatric conditions (cognitive impairment and depressive symptoms) affects the odds of disability in older adults. Methods: We analyzed data from a nationally representative sample of people aged 65years and over (n=2727) participating in the 2005 National Health Interview Survey in Taiwan. A total of 473 participants had a history of self-reported physician diagnosed diabetes. Disability was defined as reporting limitations in one or more tasks of activities of daily living (ADL), instrumental activities of daily living (IADL) or general physical activities (GPA). The Mini-Mental State Examination was used to assess cognitive function. The Center for Epidemiologic Studies Depression Scale was used to assess depressive symptoms. Results: After adjustment for other factors, cardiovascular diseases and geriatric conditions independently contributed to the excess odds of disability among participants with diabetes. Participants who had diabetes combined with cardiovascular diseases and geriatric conditions had odds ratios for ADL, IADL and GPA disability of 18.02 (95% CI 5.13-63.34), 7.95 (95% CI 4.07-15.50) and 5.89 (95% CI 3.19-10.90), respectively. Conclusion: Our results highlight the high prevalence of co-occurrence of cardiovascular diseases with geriatric conditions in people with diabetes. Furthermore, the combined presence of these diseases and conditions is strongly associated with an excess odds of disability. These findings highlight the critical importance of preventing cardiovascular disease morbidity, and improving depressed mood and cognitive function in order to reduce disability risk in older adults with diabetes. Geriatr Gerontol Int 2013; 13: 563-570.