Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases.
Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases.
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DOI：
10.3390/jcm10040581
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发表时间：
2021-02-04
影响因子：
3.9
通讯作者：
Klugar M
中科院分区：
文献类型：
--
作者：
Hocková B;Riad A;Valky J;Šulajová Z;Stebel A;Slávik R;Bečková Z;Pokorná A;Klugarová J;Klugar M
背景：冠状病毒病（COVID-19）危重患者入住重症监护病房（icu），易发生各种危及生命或导致长期并发症的并发症。COVID-19口腔粘膜皮肤并发症的病理生理过程和流行病学意义需要多学科管理和研究；因此，本研究的目的是评估COVID-19重症患者口腔并发症的患病率和特点。方法：对斯洛伐克班斯卡比斯特里察ICU收治的COVID-19危重症患者的临床和微生物学特征进行描述。此外，我们回顾了Ovid MEDLINE®、Embase、Cochrane Library和谷歌Scholar中关于COVID-19 ICU患者口腔粘膜皮肤并发症的现有证据。结果：我院ICU重症患者9例中有3例（33.3%）出现口腔并发症，包括出血性溃疡和影响唇舌的坏死性溃疡。微生物学评估显示机会致病菌的存在，证实了合并感染的可能性。回顾目前的文献，据报道，210名危重患者因在ICU环境中住院而出现口腔并发症。口腔周围压力溃疡是最常见的并发症，其次是口腔念珠菌病，疱疹和出血性溃疡，以及急性发作的大舌漏。除免疫抑制药物外，长时间俯卧位和机械通气装置是口腔并发症的主要危险因素。结论：强烈提倡采用多学科方法对COVID-19患者进行监测和管理，建议将皮肤科和口腔保健专家和护士整合到ICU团队中。
Background: The critically ill patients suffering from coronavirus disease (COVID-19) and admitted to the intensive care units (ICUs) are susceptible to a wide array of complications that can be life-threatening or impose them to long-term complications. The COVID-19 oral mucocutaneous complications require multidisciplinary management and research for their pathophysiological course and epidemiological significance; therefore, the objective of this study was to evaluate the prevalence and characteristics of the critically ill COVID-19 patients with oral complications. Methods: We described the clinical and microbiological characteristics of the critically ill COVID-19 patients in our ICU department (Banska Bystrica, Slovakia). In addition, we reviewed the current body of evidence in Ovid MEDLINE®, Embase, Cochrane Library, and Google Scholar for the oral mucocutaneous complications of ICU patients with COVID-19. Results: Three out of nine critically ill patients (33.3%) in our ICU department presented with oral complications including haemorrhagic ulcers and necrotic ulcers affecting the lips and tongue. The microbiological assessment revealed the presence of opportunistic pathogens, confirming the possibility of co-infection. On reviewing the current literature, two hundred ten critically ill patients were reported to have oral complications due to their stay in the ICU setting. Perioral pressure ulcers were the most common complication, followed by oral candidiasis, herpetic and haemorrhagic ulcers, and acute onset macroglossia. The prolonged prone positioning and mechanical ventilation devices were the primary risk factors for those oral complications, in addition to the immunosuppressive drugs. Conclusions: The multidisciplinary approach is strongly advocated for monitoring and management of COVID-19 patients, thus implying that dermatology and oral healthcare specialists and nurses should be integrated within the ICU teams.
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影响因子：
1.9
作者：
Moore, Zena;Patton, Declan;O'Connor, Tom
通讯作者：
O'Connor, Tom
DOI：
10.1097/won.0000000000000689
发表时间：
2020-09-01
影响因子：
2.6
作者：
Martel, Tanya;Orgill, Dennis P.
通讯作者：
Orgill, Dennis P.
DOI：
10.1097/won.0000000000000344
发表时间：
2017-07-01
影响因子：
2.6
作者：
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通讯作者：
Beeckman, Dimitri
DOI：
10.1016/s1473-3099(20)30948-8
发表时间：
2021-01
期刊：
The Lancet. Infectious diseases
影响因子：
--
作者：
Holt E
通讯作者：
Holt E
影响因子：
0.9
作者：
Andrews, Erickson;Lezotte, Jonathan;Ackerman, Adam M.
通讯作者：
Ackerman, Adam M.