Outcome of papillary thyroid microcarcinoma: Study of 1,990 cases
Outcome of papillary thyroid microcarcinoma: Study of 1,990 cases
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DOI：
10.3892/mco.2015.495
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发表时间：
2015-05-01
影响因子：
1.2
通讯作者：
Li, Li
中科院分区：
文献类型：
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作者：
Lu, Zhong-Zhi;Zhang, Yan;Li, Li
本研究通过分析甲状腺微小乳头状癌（PTMC）患者颈部淋巴结转移的高危因素，探讨PTMC患者预防性颈淋巴结清扫的必要性。临床病理资料回顾了2013年1月至2014年1月诊断的1990例患者。数据包括患者性别、年龄、肿瘤大小、多灶性、肿瘤病理分期、双侧甲状腺癌、亚型、BRAF(V600E)突变、人类端粒酶逆转录酶(hTERT)、甲状腺外侵犯和颈部淋巴结转移等信息。单因素分析（χ2检验）显示，多种因素与PTMC颈部淋巴结转移显着相关（P
The present study examines the requirement of prophylactic neck node dissection in papillary thyroid microcarcinoma (PTMC) patients by analyzing high-risk factors of neck lymph node metastasis in PTMC. The clinical pathological data was a review of 1,990 patients diagnosed between January 2013 and January 2014. The data included information on patient gender, age, tumor size, multifocal, tumor pathological staging, bilateral thyroid cancer, the subtypes, BRAF(V600E) mutation, human telomerase reverse transcriptase (hTERT), extrathyroidal invasion and neck lymph node metastasis. The univariate analysis (chi(2) test) showed that a number of factors were significantly associated with neck lymph node metastasis in PTMC (P